|
Associate Professor of Biological
Sciences, Ph.D. Molecular
and Cellular Pathology 2002: University of Wisconsin-Madison. Dr. Mothé
started her appointment at CSUSM in Fall 2003. Dr. Mothé conducted her
postdoctoral work at Epimmune, Inc in San Diego, CA. Her areas of
specialization are immunology and virology, with research interests in
designing novel vaccines for rapidly mutating pathogens, including HIV
and SIV.
Research Students (dates research
conducted in lab)
Ryan Henderson (Undergraduate and Master’s student, 2009- present)
Carol Dale (Undergraduate Student,
2009- present)
Daniel Wambua (Undergraduate Student,
2008- present)
Larissa D’Andrea (Master’s student,
2007- present)
Christopher Solomon (Master’s
student, 2007- present)
Jessica Berry (Undergraduate and
Master’s student, 2004- present)
Sergio Ita (Undergraduate student,
2007-2008) currently in Ph.D. program in Virology at Harvard University
Travis Nesbit (Undergraduate student,
2005-2008) currently in medical school at UC-Irvine
Courtney Dow (Master’s student,
2005-2008) currently part-time research technician for lab
Linda Villa (Undergraduate student,
2005-2007) currently in Ph.D. program at Virginia Tech
Alena Christina Ramirez
(Undergraduate student, 2004-2007) currently in Ph.D. program at the
Ohio State University
Javier Fernandez (Master’s student,
2005-2007)
Scott Worsley (Master’s student,
2004-2006)
Claudia Pawlowski (Undergraduate
student, 2004-2005)
Cynthia Basa-Morales (Undergraduate student, 2004-2005)
Barbara Stewart (Master’s student,
2004-2005) currently in Ph.D. program in Biodefense at SUNY-Albany
Stephanie Warsheski (Undergraduate
student, 2004-2005) completed 4th year of medical school and doing my
clinical rotations in New York. Planning on matching in 2010 and
hopefully get a residency in surgery or ob/gyn (updated 10/2009)
Melissa Thompson (Undergraduate
student, 2004-2005) completed Physician’s Assistant program in
Pennsylvania
Stephanie Stogiera (Undergraduate
student, 2003-2005) entered Ph.D. program at the University of Michigan
PUBLICATIONS (from 2005-present) for
complete list, click on link below
Walsh, S.R., Gillis, J.,
Peters, B., Mothé, B.R., Sidney, J., Sette, A., Johnson,
R.P. Diverse recognition of conserved orthopoxvirus CD8+ T cell
epitopes in vaccinated rhesus macaques. Vaccine. 2009 Jun
14. [Epub ahead of print]
Dow, C. #,
Oseroff, C., Peters, B., Nance-Sotelo, C. #,
Sidney, J., Buchmeier, M., Sette, A., Mothé, B.R.
Lymphocytic choriomeningitis virus infection yields overlapping
CD4+ and CD8+ T-cell responses. Journal of Virology. 2008
Dec;82(23):11734-41. Epub 2008 Oct 1.
Wang, P.,
Sidney, J., Dow, C.
#,
Mothé, B., Sette, A., Peters, B. A systematic assessment
of MHC class II peptide binding predictions and evaluation of a
consensus approach. PLoS Comput Biol. 2008 Apr
4;4(4):e1000048.
Schneidewind,
A., Brockman, M.A., Sidney, J., Wang, Y.E., Chen, H., Suscovich,
T.J., Li, B., Adam, R.I., Allgaier, R.L., Mothé, B.R.,
Kuntzen, T., Oniangue-Ndza, C., Trocha, A., Yu, X.G., Brander,
C., Sette, A., Walker, B.D., Allen, T.M. Structural and
Functional Constraints Limit Options for CTL Escape in the
Immunodominant HLA-B27 Restricted Epitope in HIV-1 Capsid.
Journal of Virology. 2008 Jun;82(11):5594-605. Epub 2008 Apr
2.
Mothé, B.R.,
Stewart, B.#, Oseroff, C., Bui, H.-H.,
Stogiera, S.#, Garcia, Z., Dow, C.,
Rodriguez-Carreno, M.P., Kotturi, M., Pasquetto, V., Botten, J.,
Crotty, S., Grey, H., Janssen, E., Buchmeier, M., Sette, A.
Chronic Lymphocytic Choriomeningitis
Virus Infection Actively Down-Regulates CD4+ T Cell Responses
Directed against a Broad Range of Epitopes. Journal of
Immunology. 2007 Jul 15;179(2):1058-67.
Bui, H.H.,
Botten, J., Fusseder, N., Pasquetto, V., Mothé, B.,
Buchmeier, M.J., Sette, A. Protein sequence database for
pathogenic arenaviruses. Immunome Res. 2007 Feb 8;3:1.
Botten, J., Alexander, J.,
Pasquetto, V., Sidney, J., Barrowman, P., Ting, J., Peters, B.,
Southwood, S., Stewart#, B., Rodriguez-Carreno,
M.P., Mothé, B., Whitton, J.L., Sette, A., Buchmeier, M.J.
Identification of protective Lassa virus epitopes that are
restricted by HLA-A2.
Journal of Virology.
2006 Sep;80(17):8351-61.
Lichterfeld, M., Williams,
K.L., Mui, S.K., Shah, S.S., Mothé, B.R., Sette, A., Kim,
A., Johnston, M.N., Burgett, N., Frahm, N., Cohen, D., Brander,
C., Rosenberg, E.S., Walker, B.D., Altfeld, M., Yu, X.G.T cell
receptor cross-recognition of an HIV-1 CD8+ T cell epitope
presented by closely related alleles from the HLA-A3 superfamily.
International
Immunology. 2006
Jul;18(7):1179-88. Epub 2006 Jun 13.
Fuller, D.H., Wu, M.S.,
McMahon, C.W., Rajakumar, P.A., Shipley, T., Fuller, J.T.,
Allen, T.M., Trichel, A.M., Mothé, B.R.,
Rudersdorf, R., Guzman, J., Haynes, J.R., Watkins, D.I.,
Murphey-Corb, M. Therapeutic DNA immunization induces persistent
control of simian AIDS after discontinuation of antiretroviral
therapy.
Virology.
2006 Apr 25;348(1):200-15. Epub 2006 Jan 24.
Schulze zur Wiesch, J.,
Lauer, G.M,, Day, C.L,, Kim, A.Y., Ouchi, K., Duncan, J.E.,
Wurcel, A.G., Timm, J., Jones, A.M., Mothé, B., Allen,
T.M., McGovern, B., Lewis-Ximenez, L., Sidney, J., Sette, A.,
Chung, R.T., Walker, B.D. Broad repertoire of the CD4+ Th cell
response in spontaneously controlled hepatitis C virus infection
includes dominant and highly promiscuous epitopes. Journal of
Immunology. 2005 Sep 15;175(6):3603-13.
Peters, B., Bui, H.H.,
Sidney, J., Weng, Z., Loffredo, J.T., Watkins, D.I., Mothé,
B.R., Sette, A. A computational resource for the prediction
of peptide binding to Indian rhesus macaque MHC class I
molecules. Vaccine. 2005 Nov 1;23(45):5212-24. Epub 2005
Aug 18.
Geisbert, T.W., Jones, S.,
Fritz, E.A., Shurtleff, A.C., Geisbert, J.B., Liebscher, R.,
Grolla, A., Stroher, U., Fernando, L., Daddario, K.M., Guttieri,
M.C., Mothe, B.R., Larsen, T., Hensley, L.E., Jahrling,
P.B., Feldmann, H. Development of a new vaccine for the
prevention of Lassa fever. PLoS Med. 2005 Jun;2(6):e183. Epub
2005 Jun 28.
Bui, H.H., Sidney, J., Peters, B., Sathiamurthy, M., Sinichi,
A., Purton, K.A., Mothe, B.R., Chisari, F.V., Watkins,
D.I., Sette, A. Automated generation and evaluation of specific
MHC binding predictive tools: ARB matrix applications.
Immunogenetics. 2005 Jun;57(5):304-14. Epub 2005 May 3.
Altfeld, M., Allen, T.M., Kalife, E., Frahm, N., Addo, M.M.,
Mothe, B.R., Rathod, A., Reyor, L., Harlow, J., Yu, X.,
Perkins, B., Sidney, J., Alter, G., Lichterfeld, M., Sette, A.,
Rosenberg, E.S., Goulder, P.J.R., Brander, C., Walker, B.D. The
majority of currently circulating HIV-1 clade B viruses fail to
prime CTL responses against an otherwise immunodominant
HLA-A2-restricted epitope. Journal of Virology. 2005
Apr;79(8):5000-5.
Tangri, S., Mothé, B.R., Eisenbraun, J., Sidney, J.,
Southwood, S., Briggs, K., Zinckgraf, J., Bilsel, P., Newman,
M., Chesnut, R., LiCalsi, C., Sette, A. Rationally Engineered
Therapeutic Proteins with Reduce Immunogenicity. Journal of
Immunology. 2005 Mar 15;174(6):3187-96.
Sette, A, Sidney, J., Bui, H.-H., del Guercio, M.-F., Alexander,
J., Loffredo, J., Watkins, D.I., and Mothé, B.R.
Characterization of the peptide-binding specificity of Mamu-A*11
results in the identification of SIV-derived epitopes and
interspecies cross-reactivity. Immunogenetics. 2005
Apr;57(1-2):53-68. Epub 2005 Mar 4.
Click Here To Go To Faculty Member's Home Page
Click Here for a Complete List Of Publications
|
